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MYC — STAT5A
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Mallette et al., J Biol Chem 2007
:
Intriguingly,
ca-STAT5A led to a down-regulation of
Myc and Myc targets, including CDK4, a negative regulator of Rb
Wernig et al., Blood 2008
(Cell Transformation, Neoplastic...) :
An inducible constitutively active
STAT5 mutant expressed in BaF3 cells was
sufficient to induce
Myc and Pim
Funakoshi-Tago et al., PloS one 2013
(Cell Transformation, Neoplastic) :
In the screening of genes whose expression was induced by JAK2 ( V617F ), we found the significant induction of
c-Myc mRNA expression
mediated by
STAT5 activation