Gene interactions and pathways from curated databases and text-mining

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IL31 — STAT1

Text-mined interactions from Literome

Subramaniam et al., Biochem Biophys Res Commun 1999 : Immunoprecipitation with specific antibodies followed by Western blot analysis with antiphosphotyrosine antibody has shown that in U937 cells, interleukin-17 induces time dependent stimulation of tyrosine phosphorylation of JAK 1, 2 and 3, Tyk 2 and STAT 1 , 2, 3 and 4 within 0.5 to 30 min. Interleukin-17 mediated tyrosine phosphorylation of these proteins strongly suggests that the JAK/STAT signaling pathway may play a major role in transducing signals from interleukin-17 receptors to the nucleus
Lee et al., J Exp Med 1999 : Interestingly, interleukin (IL)-7 selectively activated STAT1 and induced MHC class I in mature T but not B cells
Dambacher et al., Gut 2007 (Cytomegalovirus Infections...) : Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease ... IL31 mediates ERK-1/2, Akt, STAT1 , and STAT3 activation in IEC resulting in enhanced IEC migration
Kasraie et al., Allergy 2013 : Interleukin-31 strongly activated STAT-1 and 5 but not STAT-3 in human macrophages after up-regulation of IL-31 receptor with staphylococcal exotoxins