Gene interactions and pathways from curated databases and text-mining

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IL18 — NR3C2

Text-mined interactions from Literome

Kohka et al., J Interferon Cytokine Res 1999 : Involvement of interleukin-18 (IL-18) in mixed lymphocyte reactions (MLR)
Itoh et al., Transplantation 2002 : In the present study, we examined the effect of IL-18 on human mixed lymphocyte reaction (MLR) , an in vitro model of acute rejection after organ transplantation ... IL-18 strongly enhanced human MLR with respect to ICAM-1 expression and cytokine production ... The fact that histamine could inhibit the IL-18 stimulated MLR implies that immunomodulation by histamine and selective H2-receptor agonists may have an important role in future immunosuppressive strategies
Aaron et al., Clin Exp Immunol 1988 : T cell blast stimulation of MLR : role of interleukin 1 and interleukin 2