Gene interactions and pathways from curated databases and text-mining

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JUN — POMC

Text-mined interactions from Literome

Iwasaki et al., Am J Physiol Endocrinol Metab 2007 : The effects were promoter specific because AICAR enhanced the AP1 mediated POMC promoter activities but did not influence other transcription factor induced transcription
Reiter et al., Am J Physiol Endocrinol Metab 2011 : SGK1 overexpression increased CREB- and activator protein-1 dependent transcription, POMC transcription, and ACTH secretion but did not influence intracellular cAMP levels