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CD4 — PDCD1LG2

Pathways - manually collected, often from reviews:

• Reactome Reaction: CD4 → PDCD1LG2 (reaction) Carter et al., Immunol Res 2003, Sheppard et al., FEBS Lett 2004, Keir et al., Annu Rev Immunol 2008, Fife et al., Immunol Rev 2008

Text-mined interactions from Literome

Pfistershammer et al., Eur J Immunol 2006 : PD-L2 inhibition affected CD4+ and CD8+ T cells and was not abrogated by costimulation via CD28
Kuipers et al., Eur J Immunol 2006 : In this study we examined the role of PD-L1 and PD-L2 expressed by DC in naïve CD4+ T cell activation in a more physiologically relevant model system, using OVA-specific T cells in combination with various levels of TCR stimulation
Zhang et al., J Nephrol 2006 : Coculture experiments were performed to confirm the role of TEC related B7-DC in regulating CD4+T-cell activation