◀ Back to ETS1

DAXX — ETS1

Pathways - manually collected, often from reviews:

• FastForward regulation: ETS1 → DAXX (transcriptional regulation, unknown) Hollenhorst et al., Genes Dev 2007
  Evidence: DNABINDING

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: ETS1 — DAXX Li et al., Oncogene 2000*
• IRef Bind_translation Interaction: ETS1 — DAXX (two hybrid) Li et al., Oncogene 2000*
• IRef Bind_translation Interaction: ETS1 — DAXX (affinity chromatography technology) Li et al., Oncogene 2000*
• IRef Bind_translation Interaction: ETS1 — DAXX (unspecified method) Li et al., Oncogene 2000*
• IRef Biogrid Interaction: DAXX — ETS1 (direct interaction, pull down) Li et al., Oncogene 2000*
• IRef Biogrid Interaction: DAXX — ETS1 (direct interaction, two hybrid) Li et al., Oncogene 2000*
• IRef Biogrid Interaction: DAXX — ETS1 (physical association, affinity chromatography technology) Murakami et al., J Biol Chem 2006*
• IRef Hprd Interaction: ETS1 — DAXX (in vitro) Li et al., Oncogene 2000*
• IRef Hprd Interaction: ETS1 — DAXX (two hybrid) Li et al., Oncogene 2000*
• IRef Intact Interaction: ETS1 — DAXX (colocalization, fluorescence microscopy) Li et al., Oncogene 2000*
• IRef Intact Interaction: ETS1 — DAXX (physical association, two hybrid) Li et al., Oncogene 2000*
• IRef Intact Interaction: ETS1 — DAXX (physical association, two hybrid) Yordy et al., Oncogene 2004*
• IRef Intact Interaction: ETS1 — DAXX (direct interaction, pull down) Li et al., Oncogene 2000*
• IRef Mppi Interaction: ETS1 — DAXX (two hybrid) Li et al., Oncogene 2000*
• IRef Mppi Interaction: ETS1 — DAXX (copurification) Li et al., Oncogene 2000*
• IRef Ophid Interaction: ETS1 — DAXX (aggregation, confirmational text mining) Li et al., Oncogene 2000*
• IRef Ophid Interaction: ETS1 — DAXX (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Li et al., Oncogene 2000 (Adenocarcinoma...) : EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes
Kwon et al., J Biol Chem 2006 : Expression of SPOP with Cul3 reversed Daxx mediated repression of ETS1- and p53 dependent transcription, and short hairpin RNA mediated knock down of SPOP blocked the recovery of their transcriptional activation
Murakami et al., J Biol Chem 2006 : Co-immunoprecipitation and immunoblotting experiments suggested that LANA bound Daxx to inhibit the interaction between Daxx and Ets-1
Li et al., Lab Invest 2013 (Neuroblastoma) : We confirmed that Sp1 and Ets1 bound to the core promoter region of DAXX and stimulated DAXX transcriptional activity