Gene interactions and pathways from curated databases and text-mining

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CEACAM1 — NFKB1

Text-mined interactions from Literome

Muenzner et al., J Biol Chem 2001 : Gonococcal infection activated a nuclear factor-kappaB (NF-kappaB) heterodimer consisting of p50 and p65, and inhibitors that prevent the nuclear translocation of activated NF-kappaB complex inhibited CEACAM1 transcript expression ... The regulation of CEACAM1 expression by NF-kappaB also implies a broader role for this receptor in the general inflammatory response to infection
Muenzner et al., J Biol Chem 2002 : N. gonorrhoeae triggered CEACAM1 up-regulation involves activation of the transcription factor nuclear factor kappaB (NF-kappaB) , which translocates as a p50/p65 heterodimer into the nucleus, and an NF-kappaB-specific inhibitory peptide inhibited CEACAM1-receptor up-regulation in N. gonorrhoeae infected HOSE cells
Slevogt et al., Nat Immunol 2008 : Here we demonstrate that the interaction of CEACAM1 with ubiquitous surface protein A1 expressed on M. catarrhalis or with opacity associated proteins on N. meningitidis resulted in reduced Toll-like receptor 2-initiated transcription factor NF-kappaB dependent inflammatory responses of primary pulmonary epithelial cells