Gene interactions and pathways from curated databases and text-mining

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KLF5 — NFKB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Chanchevalap et al., Nucleic Acids Res 2006 : Importantly, suppression of KLF5 by small interfering RNA ( siRNA ) resulted in a reduction in p50 and p65 subunit mRNA levels and NF-kappaB DNA binding activity in response to LPS
Lin et al., Arterioscler Thromb Vasc Biol 2006 : Mechanistically, KLF2 inhibits PAR-1 expression and, as a consequence, thrombin mediated nuclear factor kappaB (NF-kappaB) nuclear accumulation and DNA binding
Das et al., Proc Natl Acad Sci U S A 2006 (Atherosclerosis...) : Mechanistically, KLF2 inhibits the transcriptional activity of both NF-kappaB and activator protein 1, in part by means of recruitment of transcriptional coactivator p300/CBP associated factor