Gene interactions and pathways from curated databases and text-mining

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CA1 — TNF

Text-mined interactions from Literome

Meldrum et al., J Surg Res 2003 (Myocardial Ischemia) : We hypothesized that CAB with cardiopulmonary bypass ( `` on-pump '' ) activates human myocardial NF-kappaB and increases TNF in the heart
Ju et al., Eur J Cancer 2012 (Arthritis, Experimental...) : The results showed that CAI could inhibit tumour necrosis factor-a (TNF-a) production in macrophages in various environments, including those isolated from peritoneal cavity of adjuvant induced arthritis ( AA ) rats, from Lewis lung carcinoma ( LLC ) transplanted tumours and those induced by LLC cells in vitro ... Over all, we found CAI could act on macrophages and regulate the production of TNF-a not only in inflammatory diseases but also in tumour microenvironment, which might be another anti-tumour mechanism of CAI
Turpin et al., J Leukoc Biol 1990 : TNF release ( L929 cytolytic assay ) in the presence of cAB occurred during the first 3 days of in vitro culture
Guo et al., J Pharmacol Exp Ther 2012 (Colitis...) : CAI inhibited the production of TNF-a , IL-1ß, and IL-6 in serum, supernatant of peritoneal macrophages, and lamina propria
Yamato et al., Blood 1989 : TNF did not increase Cai++ and, moreover, was able to stimulate accumulation of GM-CSF mRNA in the absence of extracellular Ca++ ... Our studies show that TNF appears to increase levels of GM-CSF mRNA independent of protein kinase C activity or levels of Cai++
Watanabe et al., J Biochem 1996 : These results indicate that the transient increase of [ Ca]i plays a role in LPS induced expression of TNF-alpha by the macrophage cell line
West et al., Shock 1998 : We sought to determine whether carbonic anhydrase inhibition with acetazolamide would prevent CO2 mediated inhibition of LPS stimulated TNF release