Gene interactions and pathways from curated databases and text-mining

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CYCS — TNF

Text-mined interactions from Literome

Rokhlin et al., Oncogene 2000 (Prostatic Neoplasms) : Cytochrome c release was induced by TNF-alpha treatment in both cell lines, but caspase-9 was not activated
Tafani et al., Am J Pathol 2000 : Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition