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EGF — TNF

Text-mined interactions from Literome

Perez et al., Oncogene 1999 : In this report, the effects of TNF on EGF receptor tyrosine phosphorylation in ME-180 cell variants selected for apoptotic sensitivity (Sen) or resistance ( Res ) to TNF, previously shown to differentially express EGFr, were examined
Paul et al., J Biol Chem 2000 (MAP Kinase Signaling System) : In the EAhy926 endothelial cell line, UTP, ATP, and forskolin, but not UDP and epidermal growth factor , inhibited tumor necrosis factor alpha (TNFalpha)- and sorbitol stimulation of the stress activated protein kinases, JNK, and p38 mitogen activated protein ( MAP ) kinase, and MAPKAP kinase-2, the downstream target of p38 MAP kinase
Chevalier et al., Eur J Biochem 2000 : However, both EGF and nafenopin require tumour necrosis factor alpha (TNFalpha) signalling to induce DNA replication
Subauste et al., Int Immunopharmacol 2001 : Moreover, TNF-alpha increased viral replication in the presence of EGF but not TGF-alpha
Deaciuc et al., Alcohol Clin Exp Res 2002 (Liver Diseases, Alcoholic) : EGF did not affect liver mRNA expression of TNF-alpha , IL-1beta, IL-6, and IL-10, which suggested that these cytokines were not involved in EGF protective effect
Akca et al., Growth Factors 2003 (Uterine Cervical Neoplasms) : Suppression of TNF-alpha mediated apoptosis by EGF in TNF-alpha sensitive human cervical carcinoma cell line
Maruo et al., Steroids 2003 (Leiomyoma...) : Treatment with P4 augmented EGF and Bcl-2 protein expression, but inhibited IGF-I and TNFalpha expression in cultured leiomyoma cells
Valyi-Nagy et al., J Invest Dermatol 1992 : Human ( hu ) recombinant ( r ) tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma induced EGF/TGF-alpha receptor and TGF-alpha expression by keratinocytes as determined by immunohistochemistry
Lahat et al., Cancer 1992 (Thyroid Neoplasms) : In a fifth neoplastic cell line ( papillary carcinoma, NPA ) that constitutively expressed surface DR, its expression was inhibited by both alpha-IFN and TNF-alpha and was not affected by EGF
Yoshizumi et al., J Biol Chem 1992 : Tumor necrosis factor increases transcription of the heparin binding epidermal growth factor-like growth factor gene in vascular endothelial cells
Osawa et al., Am J Physiol Lung Cell Mol Physiol 2007 : In other cell types, TNF-alpha receptors transactivate the EGF receptor, which activates raf-1 kinase
Miyazaki et al., Helicobacter 2007 (Gastritis...) : Moreover, the methylation was induced by TNFalpha , MG132, and EGF treatment, and DNA methyltransferase activity was induced by EGF treatment in MKN-1 cells
McElroy et al., Am J Physiol Gastrointest Liver Physiol 2008 : Tumor necrosis factor inhibits ligand stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism
Takahashi et al., Indian J Dermatol 2009 : Furthermore, TNF-alpha induced secretion of IL-6, IL-8, EGF , HGF, TGF-alpha, epiregulin, and amphiregulin were compared among these keratinocytes ... The significant induction of TNF-alpha increased IL-6, IL-8, EGF , HGF, TGF-alpha, epiregulin, and amphiregulin, but the increase in these cytokines and growth factors were not different among normal skin, uninvolved, and involved psoriasis
Maillé et al., Am J Physiol Lung Cell Mol Physiol 2011 (Cystic Fibrosis) : First, we discerned that TNF-a induced metalloproteinase-9 release, epidermal growth factor (EGF) shedding, and subsequent EGF receptor transactivation
Scalabrino et al., Exp Neurol 2012 (Disease Models, Animal...) : However, as it is known that Cbl deficiency damages myelin by increasing tumor necrosis factor (TNF)-a and decreasing epidermal growth factor (EGF) levels in rat spinal cord ( SC ), and that TNF-a and EGF regulate PrP ( C ) expression in vitro, we investigated whether Cbl deficiency modifies SC PrP ( C ) and PrP ( C ) -mRNA levels in Cbl-D rats
Katoh et al., Biochem Biophys Res Commun 1990 (Translocation, Genetic) : Tumor necrosis factor (TNF) caused an inhibition of 125I labeled epidermal growth factor [ ( 125I ] EGF ) binding to its receptors of human amniotic ( WISH ) cells at 5 min after addition of TNF, which reached a maximal level ( 60-70 % reduction ) after 15-30 min and declined thereafter ... Furthermore, prolonged incubation of WISH cells with 12-O-tetradecanoylphorbol 13 acetate ( TPA ) diminished the TPA effect on the inhibition of EGF binding to the cells due to the desensitization of protein kinase C ; however, TNF still reduced the EGF binding to the cells pretreated with TPA for a long time
Donato et al., J Biol Chem 1989 (Carcinoma, Squamous Cell...) : Quantitation of receptors expressed on the surface of ME-180 and T24 cells demonstrated a 3-fold difference between the number of EGF binding sites on T24 ( 100,000 ) versus ME-180 cells ( 300,000 ), suggesting the relative abundance of EGF receptor does not solely account for differential effects of TNF on EGF receptor activation in these two cell lines ... These results suggest that TNF induced modulation of EGF receptor occurs through a unique mechanism and may play a role in the cytotoxic actions of TNF
Palombella et al., J Cell Physiol 1988 : We have previously shown that tumor necrosis factor (TNF) can increase the number of epidermal growth factor (EGF) receptors on human FS-4 fibroblasts and that this increase may be related to the mitogenic action of TNF in these cells
Palombella et al., J Biol Chem 1987 : Tumor necrosis factor increases the number of epidermal growth factor receptors on human fibroblasts ... Here we show that human recombinant TNF can increase the binding of epidermal growth factor (EGF) to these cells ... TNF increased EGF binding with a dose-response relationship similar to that reported earlier for the mitogenic action
Sedlak et al., Chemotherapy 1994 (Breast Neoplasms) : IL-1 beta and tumor necrosis factor alpha (TNF-alpha) increased the EGF receptor surface expression only on BT-20 breast carcinoma cells
Mishra et al., Lymphokine Cytokine Res 1994 : Immunoblot analysis revealed that TNF enhanced tyrosyl phosphorylation of the epidermal growth factor receptor (EGFR) only in TNF-sensitive cell lines
Pusztai et al., Cytokine 1993 (Breast Neoplasms) : The effect of epidermal growth factor (EGF) , basic fibroblast growth factor (bFGF) and insulin-like growth factor-1 (IGF-1) on the cytostatic activity of tumour necrosis factor-alpha (TNF-alpha) was studied on the breast cancer cell line, T47D
Cianciarulo et al., In Vitro Cell Dev Biol Anim 1993 : Effects of tumor necrosis factor and interferon-beta on proliferation and epidermal growth factor binding in young and senescent WI-38 cells
Melnick et al., Dev Dyn 1996 : Glucocorticoids, tumor necrosis factor-alpha , and epidermal growth factor regulation of pulmonary morphogenesis : a multivariate in vitro analysis of their related actions
Wang et al., Anticancer Res 1996 : In this study, we investigated the modulatory effect of TNF alpha on EGF receptor of a human hepatocellular carcinoma cell line-HepG2 ... The modulatory effect of TNF alpha on the EGF receptor of HepG2 cells exhibited its unique characteristics in comparison with the previous reports on other tumor cells ... Therefore, the effect of TNF alpha on EGF receptor tyrosine phosphorylation in HepG2 cells was due to enhancing the receptor 's response to EGF