Gene interactions and pathways from curated databases and text-mining

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IFNG — IL1R1

Text-mined interactions from Literome

Hu et al., J Immunol 2005 (Inflammation) : IFN-gamma mediated down-regulation of IL-1R type I expression was dependent on Stat1, a transcription factor typically considered to be a key mediator of macrophage activation by IFNs
Groves et al., Am J Pathol 1994 (Psoriasis) : The in vitro induction of keratinocyte IL-1R by interferon-gamma suggests that this cytokine may be involved in the induction of type II IL-1R in inflammatory skin disease
Dickensheets et al., J Immunol 1997 : IFN-gamma has been shown to inhibit induction of CD23 and 15-lipoxygenase in monocytes ; however, the effects of IFN-gamma on type I and type II IL-1R gene expression have not been defined ... We examined the effects of IFN-gamma on both basal and IL-4/IL-13 induced IL-1R gene expression in primary monocytes
Panja et al., J Immunol 1998 (Inflammation...) : Expression of IL-1R and IL-6R was enhanced by LPS and IFN-gamma