Sonobe et al., Inflamm Res 2004
:
Depletion of the H1R resulted in decreases in the release of IL-2 and IL-10 from both CD4+ and CD8+ cells and increases in the release of IL-4 from CD4+ T cells and IFN-gamma from CD8+ cells
Noubade et al., J Clin Invest 2007
(Encephalomyelitis, Autoimmune, Experimental...) :
Here we showed that expression of H1R in naive CD4+ T cells was required for maximal IFN-gamma production but was dispensable for proliferation