Gene interactions and pathways from curated databases and text-mining

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ABL1 — DOK1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Dunant et al., Cell Signal 2000 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Expression of Bcr-Abl induced tyrosine phosphorylation of both Dok1 and SHIP1 and the formation of a Dok1/SHIP1 complex
Master et al., J Biol Chem 2003 : Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization
Oki et al., Cell cycle (Georgetown, Tex.) 2005 (Cell Transformation, Neoplastic...) : These data indicate that both SHIP and Dok1 functionally regulate the activation of Ras-Erk pathway by v-Abl and affect the mitogenic activity of v-Abl transformed bone marrow cells