Gene interactions and pathways from curated databases and text-mining

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MMP12 — NPS

Text-mined interactions from Literome

Luo et al., J Control Release 2010 (Prostatic Neoplasms) : The inhibition of caspase-2 activation by small interfering RNA ( siRNA ) knockdown resulted in the significant inhibition of Dtxl-NPs induced disruption of MMP and Dtxl-NPs induced apoptosis, indicating that the activation of caspase-2 was the critical event before the mitochondrial depolarization in the PC3 cells
Roulet et al., BMC pulmonary medicine 2012 (Pneumonia...) : TiO2 NPs per se did not modify the parameters investigated, but CB NPs increased perivascular/peribronchial infiltration, and macrophage MMP-12 expression, without inducing emphysema
Sehgal et al., Cancer Res 1998 (Adenocarcinoma...) : These data indicate that neuropeptides can regulate MMP activity, which, in turn, could facilitate prostate cancer progression