Gene interactions and pathways from curated databases and text-mining

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ARF5 — JUN

Text-mined interactions from Literome

Kim et al., J Biol Chem 2003 : In addition, ARF4 mediated PLD2 activation leads to dramatic activation of the transcription factor activator protein 1 (AP-1) , and, importantly, ARF4 activity is required for EGF induced activation of cellular AP-1
Ameyar-Zazoua et al., Oncogene 2005 : The ARF promoter is regulated specifically by AP-1 heterodimers containing Fra-1 ... Conversely, inhibition of c-Jun or Fra-1 protein levels resulted in decreased ARF expression ... Thus, AP-1 heterodimers may contribute to the regulation of ARF expression upon oncogenic signaling
West et al., J Cell Biol 1997 : Surprisingly, however, neither PLD nor neomycin has any effect on the recruitment of AP-1 adaptors onto the TGN, even though AP-1 recruitment is ARF mediated