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RHO — TAT

Text-mined interactions from Literome

Wu et al., J Biol Chem 2007 (MAP Kinase Signaling System) : Within 2 min, Tat activated both Ras and Rho GTPases in endothelial cells, leading to ERK phosphorylation by 10 min. Notably, Rac1 was necessary for downstream activation of RhoA and both Rac1 and RhoA acted upstream of the Ras/ERK cassette
Zhong et al., J Neurosci 2012 : Depletion of CREB by infection of cells with specific shRNA lentiviral particles attenuated both Tat induced Rho signaling and nuclear targeting of ZO-1