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FGF2 — SPHK2
Text-mined interactions from Literome
Xu et al., Atherosclerosis 2002
:
The present study thus demonstrates that
SphK , PKC and Gi-protein activities are
required for
bFGF-mitogenic signaling in SMC
Rius et al., FEBS Lett 1997
(Pheochromocytoma) :
Nerve growth factor (NGF),
basic fibroblast growth factor (bFGF) , dibutyryl cAMP and forskolin, known differentiating agents for pheochromocytoma PC12 cells,
induced sustained activation of
sphingosine kinase , the enzyme responsible for the formation of the sphingolipid second messenger, sphingosine-1-phosphate, which mediates the mitogenic effects of certain growth factors