Gene interactions and pathways from curated databases and text-mining

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FGF2 — SPHK2

Text-mined interactions from Literome

Xu et al., Atherosclerosis 2002 : The present study thus demonstrates that SphK , PKC and Gi-protein activities are required for bFGF-mitogenic signaling in SMC
Rius et al., FEBS Lett 1997 (Pheochromocytoma) : Nerve growth factor (NGF), basic fibroblast growth factor (bFGF) , dibutyryl cAMP and forskolin, known differentiating agents for pheochromocytoma PC12 cells, induced sustained activation of sphingosine kinase , the enzyme responsible for the formation of the sphingolipid second messenger, sphingosine-1-phosphate, which mediates the mitogenic effects of certain growth factors