Gene interactions and pathways from curated databases and text-mining

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SPHK1 — SPHK2

Text-mined interactions from Literome

Sutherland et al., J Biol Chem 2006 : The calmodulin binding site of sphingosine kinase and its role in agonist dependent translocation of sphingosine kinase 1 to the plasma membrane
Li et al., Br J Haematol 2007 (Multiple Myeloma) : IL-6 stimulation or retroviral mediated overexpression of SPHK1 in MM cells resulted in increased intracellular SPHK activity and upregulation of myeloid cell leukaemia-1 (Mcl-1), leading to increased cell proliferation and survival