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IFNG — PINK1
Text-mined interactions from Literome
Oda et al., Life Sci 1999
:
Stimulation of
PPD-specific and Der f-specific T cell lines with relevant antigens
resulted in production of mostly
interferon (IFN)-gamma and of interleukin (IL)-4 and IL-5, respectively
Salem et al., Int Arch Allergy Immunol 2000
(Hypersensitivity, Delayed...) :
The analysis of production and gene expression of cytokines by DLN cells demonstrated that E2 treatment suppressed IL-2 and
IFN-gamma production in
response to
PPD in vitro
Koga et al., Eur J Dermatol 2001
(Erythema Induratum...) :
The patient 's peripheral blood mononuclear cells showed a high proliferation and produced
interferon-gamma (IFN-gamma) in
response to
purified protein derivative (PPD)
Greinert et al., J Clin Immunol 2000
(Lung Diseases...) :
For a subgroup of tuberculin skin test positive NTM patients we found significantly lower
PPD induced
IFN-gamma releases in cultured DWB ( P < 0.0002 ) and PBMC ( P < 0.0004 ) compared to MTb patients ... The four NTM patients with poor
PPD induced
IFN-gamma response hardly showed increased cytokine production on stimulation with their specific mycobacterium
Kamal et al., Clin Exp Allergy 2001
:
In addition, Ac2-26 and dexamethasone inhibited Der p-induced IL-5 release and
PPD induced
IFN-gamma release in a concentration dependent fashion
Mochida-Nishimura et al., Cell Immunol 2001
:
Both GM-Mphis and M-Mphis equally suppressed lymphocyte proliferation, but only M-Mphis suppressed
IFN-gamma production in
response to
purified protein derivative (PPD)
Barth et al., Clin Exp Immunol 2003
(Hypersensitivity, Delayed...) :
Active immunization of subject A with TT at the end of the observation period of 12 months resulted in a transient shift from type 1- to a mixed type 1/type 2-profile ( simultaneous
PPD induced
IFN-gamma- and TT-induced IL-5 production )
Brock et al., Am J Respir Crit Care Med 2004
(Tuberculosis) :
This test measures the production of
IFN-gamma in whole blood upon
stimulation with
purified protein derivative (PPD)
Yentür et al., J Neuroimmunol 2005
(Subacute Sclerosing Panencephalitis) :
Proliferation, as well as
IFN-gamma , IL-12 and IL-10 production in
response to
purified protein derivate (PPD) was impaired in SSPE patients
Okano et al., Immunology 2006
:
Furthermore, PGE2 and EP2 receptor agonist significantly inhibited interleukin-5 and
interferon-gamma production by peripheral blood mononuclear cells in
response to Cry j 1 and
PPD stimulation, respectively
Moormann et al., J Infect Dis 2007
(Burkitt Lymphoma...) :
In contrast,
IFN- gamma responses to PHA,
PPD , and Plasmodium falciparum MSP-1 peptides did not significantly differ by age
McIlleron et al., Tuberculosis (Edinb) 2007
(Tuberculosis, Pulmonary) :
In multivariate analysis of parameters at 2 months the strongest positive associations with disease free survival were
IFN-gamma response to
PPD ( p=0.002 ) and serum creatinine ( p=0.001 )
Eum et al., Diagn Microbiol Infect Dis 2008
(Tuberculosis) :
We also examined the correlation between the interferon (IFN)-gamma response to these antigens and the exposure risk to TB by evaluating antigen-specific IFN-gamma release in comparison with
IFN-gamma release in
response to
purified protein derivative (PPD) in 3 groups : medical students, nurses in a TB hospital, and TB patients
Elliott et al., J Infect Dis 2009
(HIV Infections...) :
Raw
IFN-gamma responses to RD1 antigens and
PPD corrected for pre-ART CD4 ( + ) T cell counts were higher at all time points in individuals with ART associated tuberculosis ( P < .001 ) and were associated with areas under receiver operator characteristic curves of 0.90 for RD1 ( 95 % confidence interval [ CI ], 0.78-1.00 ) and 0.92 for PPD ( 95 % CI, 0.83-1.00 ) for the diagnosis of ART associated tuberculosis
Debebe et al., J Immunoassay Immunochem 2010
:
A sharp rise in
IFN-gamma response to bovine
PPD was observed between at week 3, and then from week 3 to 7 post-vaccination, there was rapid falling of IFN-gamma response after which the response remained more or less constant in the consecutive weeks
Sartono et al., PloS one 2010
(Cicatrix) :
In a pooled analysis receiving OPV with BCG at birth was associated with significantly lower IL-13 ( p = 0.041 ) and
IFN-gamma ( p = 0.004 ) and a tendency for lower IL-10 ( p = 0.054 ) in
response to
PPD
Burl et al., PloS one 2010
(Cicatrix) :
However the IFNgamma : IL-10 ratio positively correlated with TST induration suggesting that the relationship between
PPD induced
IFNgamma and IL-10 in the peripheral blood may be important in controlling TST reactivity
Wood et al., Vet Microbiol 1994
(Tuberculosis, Bovine) :
The problem of false positive reactions, due to the cross-reactive nature of the antigen preparations used, can largely be overcome by using a comparative assay in which an animal 's
IFN-gamma response to bovine
PPD and avian PPD are compared
Jutel et al., Clin Exp Allergy 1995
:
In contrast,
PPD induced virtually only
IFN gamma secretion
Ebtekar et al., Scand J Immunol 1996
:
The PPD1 induced IL-5 production, while the
PPD2 induced high levels of
IFN-gamma
Saito et al., J Leukoc Biol 1996
(Tuberculosis) :
Our present data indicate that TNF-alpha produced by
PPD stimulated macrophages and
IFN-gamma produced by cell-cell interaction of BCG-immune T cells and antigen engulfed macrophages together activate the macrophages to produce NO
Ng et al., Vet Immunol Immunopathol 1997
(Tuberculosis, Bovine) :
Bovine
purified protein derivative (PPD) induced
interferon-gamma (IFN-gamma) and interleukin-2 (IL-2) mRNA expression was measured in peripheral blood lymphocyte cultures of cattle inoculated with Mycobacterium bovis and compared to cytokine protein levels as measured by IFN-gamma enzyme linked immunosorbent assay and IL-2 bioassay
Nakaya et al., Kekkaku 1997
(Acute Disease...) :
Interferon-gamma (IFN-gamma) and interleukin-10 (IL-10) producing ability of peripheral blood plastic-dish adherent cells and non-adherent cells obtained from patients with active pulmonary tuberculosis ( N = 17 ) and healthy controls ( N = 14 ) upon
stimulation with
purified protein derivatives (PPD) were assessed
Hata et al., Int Arch Allergy Immunol 1997
(Hypersensitivity) :
IL-4 pretreatment suppressed
PPD induced
IFNgamma and IL-5 production but enhanced ECF production
Corrigan et al., Clin Exp Immunol 1998
(Candidiasis, Vulvovaginal...) :
Interferon-gamma (IFN-gamma) production in
response to both Candida and
purified protein derivative (PPD) stimulation was significantly lower in patients compared with controls