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MMP12 — MMP3
Text-mined interactions from Literome
Tan et al., Am J Respir Cell Mol Biol 2006
(Pneumonia...) :
No increases in RNA levels of MMP-2,
MMP-9 , or MMP-8 were found, but levels of MMP-7,
MMP-12 , and MMP-13 RNA did
increase at 14 d
Choi et al., J Neurochem 2008
(Nerve Degeneration...) :
Under the cell stress condition,
MMP-3 is released as actMMP-3 rather than the proform ( proMMP-3 ), and catalytically active
MMP-3 added to the medium does not
cause cell death
Madala et al., J Immunol 2010
(Fibrosis...) :
Instead, we observed marked increases in MMP2 and MMP13 expression, suggesting that Mmp12 was promoting fibrosis by limiting the expression of specific ECM degrading MMPs. Interestingly, like
MMP12 ,
MMP13 expression was highly
dependent on IL-13 and type II-IL-4 receptor signaling
Li et al., PloS one 2012
(Disease Models, Animal...) :
Similar results were observed in the study using
MMP408 , a pharmacological
inhibitor of
MMP-12
Coker et al., Am J Physiol 1998
(Heart Failure) :
With pacing CHF, the relative abundance for MMP-1 increased to 319 +/- 94 %,
MMP-2 increased to 194 +/- 31 %, and
MMP-3 increased to 493 +/- 159 % ( all P < 0.05 )