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ENO4 — PLG
Text-mined interactions from Literome
López-Alemany et al., Am J Hematol 2003
(Adenocarcinoma...) :
In the present study we have examined the
role of
alpha-enolase in
plasminogen activation on the cell surface
Bizik et al., Cell Death Differ 2004
(Necrosis) :
We also identified
alpha-enolase mediated
plasminogen activation as the major extracellular proteolytic executor of necrotic cell death
Pancholi et al., Microb Pathog 2003
:
The increased
plasminogen binding in the
presence of free
enolase indicated the presence of an enolase/SEN-specific receptor on the pharyngeal cell surface
Sousa et al., Biochem Biophys Res Commun 2005
(MAP Kinase Signaling System) :
Plasminogen/plasmin regulates
alpha-enolase expression through the MEK/ERK pathway ... Pla mimics
Plg stimulated
alpha-ENO expression through its serine protease activity, suggesting that conversion of Plg to active Pla is required ... Altogether, our data show that
Plg/Pla regulates
alpha-ENO expression through the MEK/ERK pathway
Redlitz et al., Eur J Biochem 1995
:
Moreover, immunopurified
alpha-enolase enhanced plasminogen activation by tissue plasminogen activator and
blocked the binding of
plasminogen to alpha 2-antiplasmin, mimicking functions arising from the association of plasminogen with cells
Bergman et al., FEBS Lett 1997
(Cell Transformation, Neoplastic) :
However, no difference was observed between normal and transformed cells in formation of plasmin, suggesting that upregulation of
alpha-enolase may
contribute to an increased metabolic capacity, but not to increased
plasminogen activation