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MAPK1 — OSM

Text-mined interactions from Literome

Halfter et al., Brain Res Mol Brain Res 2000 (Glioblastoma...) : Activation of the Jak-Stat- and MAPK-pathways by oncostatin M is not sufficient to cause growth inhibition of human glioma cells ... Consistent with our recent findings, OSM treatment also induced the activation of the MAPK erk2 and the tyrosine phosphatase SHP-2 in cells of the A172, T98G and U343-MG cell lines
Thabard et al., Cytokine 2001 (MAP Kinase Signaling System...) : In OPM-2 cells, IL-6, OSM and LIF induce both signal transducers and activators of transcription ( STAT ), mitogen activated protein kinase ( MAPK ) and phosphatidylinositol 3-kinase (PI 3-K) activation
Sohara et al., J Hepatol 2002 (MAP Kinase Signaling System) : PD inhibited OSM mediated stimulation of TIMP-1 protein, mRNA, promoter activity, phosphorylation of MAPK , and TIMP-1 message stability
Langdon et al., J Immunol 2003 (Pulmonary Eosinophilia) : OSM induced ERK-1,2 and p38 mitogen activated protein kinase phosphorylation in NIH 3T3 cells, and inhibitors of ERK ( PD98059 ) or p38 ( SB203580 ) could partially reduce OSM induced eotaxin production, suggesting partial dependence on mitogen activated protein kinase signaling
Wojtal et al., Mol Biol Cell 2007 : Here, we show that oncostatin M , but not cAMP, promotes the A-kinase anchoring protein ( AKAP ) -dependent anchoring of the PKA regulatory subunit ( R ) IIalpha to subapical centrosomes and that this requires extracellular signal regulated kinase 2 activation
Salamon et al., J Allergy Clin Immunol 2008 (Sarcoidosis) : OSM was localized to the cytoplasm, and its expression was inhibited by dexamethasone and mitogen activated protein kinase inhibitors
Thoma et al., J Biol Chem 1994 : However, we found that OSM is a much more potent inducer of both mitogen activated protein kinase activity and biological response, both of which correlate with the expression of a second OSM receptor that does not bind LIF
Korzus et al., J Biol Chem 1997 : The mitogen activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element mediated activation of matrix metalloproteinase 1 gene expression
Stancato et al., Mol Cell Biol 1997 : Beta interferon and oncostatin M activate Raf-1 and mitogen activated protein kinase through a JAK1 dependent pathway ... In HeLa cells, both IFN-beta and oncostatin M (OSM) stimulated MAPK and Raf-1 enzyme activity, in addition to Stat1 and Stat3 tyrosine phosphorylation