Gene interactions and pathways from curated databases and text-mining

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PLAUR — SP1

Text-mined interactions from Literome

Zannetti et al., Biochem Pharmacol 2005 (Breast Neoplasms) : Here, we investigated whether a marked down-regulation of Sp1 activity may inhibit uPAR expression and migration ability of MDA-MB-231 breast cancer cells
Borgatti et al., Oncol Res 2005 (Carcinoma, Hepatocellular...) : Because the expression of uPAR is regulated at the level of transcription in part by Sp1 , we designed and tested transcription factors decoy molecules targeting Sp1 with the aim of inhibiting uPAR gene expression