Gene interactions and pathways from curated databases and text-mining

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MSN — RHOA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Jeon et al., J Biol Chem 2005 : Moesin phosphorylation at Thr-558 was increased after 2 min of KCl treatment, peaked at 5 min, and returned to the basal level by 60 min. KCl also activated Rac1, but not RhoA , in PC12 cells, and KCl induced moesin phosphorylation was suppressed in dominant negative Rac1 ( N17 Rac1 ) -expressed cells
Molnar et al., Mech Dev 2006 : The effects of moe mutants on Hedgehog signalling depend on the correct gene-dose of rhoA, suggesting that the requirements for Moesin in disc morphogenesis and Hh signalling in the wing disc are mediated by its regulation of RhoA activity
Wang et al., Cardiovascular diabetology 2012 : RhoA/ROCK dependent moesin phosphorylation regulates AGE induced endothelial cellular response ... This study was to investigate the involvement of RhoA/ROCK dependent moesin phosphorylation in endothelial abnormalities induced by AGEs
Oshiro et al., J Biol Chem 1998 : Here, using a site- and phosphorylation state-specific antibody, we found that the expression of dominant active RhoA in COS7 cells induced moesin phosphorylation and the formation of microvilli-like structures at apical membranes where the Thr558 phosphorylated moesin accumulated, whereas the expression of dominant negative Rho-kinase inhibited both of these processes