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F2RL3 — XRCC6
Text-mined interactions from Literome
Lova et al., J Biol Chem 2004
:
We found that, similarly to thrombin, selective stimulation of either PAR-1 or
PAR-4 by specific activating peptides
caused accumulation of GTP bound
Rap1B in a dose dependent manner ... In the presence of the ADP scavengers apyrase or phosphocreatine-phosphocreatine kinase, activation of
Rap1B induced by stimulation of either PAR-1 or
PAR-4 was totally inhibited ... Concomitant stimulation of both PAR-1 and
PAR-4 in the presence of ADP scavengers still
resulted in a strongly reduced activation of
Rap1B
Cifuni et al., Blood 2008
:
Independent roles for CalDAG-GEFI and PKC/Galphai signaling were also observed for
PAR4p induced activation of the small GTPase
Rap1 , with CalDAG-GEFI mediating the rapid but reversible activation of this small GTPase