Li et al., Circ Res 2004
(MAP Kinase Signaling System) :
PGI2 or iloprost at the IP receptor inhibited basal ERK phosphorylation with IC50 values of 10 nmol/L. Iloprost also attenuated the sustained activation of ERK induced by endothelin-1 or basic fibroblast growth factor (bFGF)
Verrière et al., J Biol Chem 2005
(MAP Kinase Signaling System) :
The dexamethasone effect on pH(i) regulation was reduced by inhibitors of adenylate cyclase, cAMP dependent protein kinase and mitogenactivated protein kinase (ERK1/2) Bernard et al., J Neurosci Res 2006
(MAP Kinase Signaling System) :
Clamping the pH(i) of OPCs at 7.15 caused a transient activation of ERK1/2 that was not observed at more acidic or alkaline values
Jackson et al., Thromb Res 2010
(MAP Kinase Signaling System) :
PGI ( 2 ) inhibited ERK/p38 ( MAPK ) phosphorylation in response to both agonists which was unaffected by a cPLA(2) inhibitor ( AACOCF ( 3 ) )
Fisher et al., American journal of physiology. Renal physiology 2012
(MAP Kinase Signaling System) :
Reduction in pH(i) induced by an NH ( 4 ) Cl prepulse also increased the phosphorylation of Pyk2, ERK1/2 , and p38