Gene interactions and pathways from curated databases and text-mining

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IFNG — PPARA

Text-mined interactions from Literome

Daynes et al., Antioxid Redox Signal 2003 : Lower PPARalpha levels are present in aged CD4+ T cells, and appear responsible for the suppressed interleukin-2 and exaggerated IFNgamma responses by these cells
Straus et al., Trends Immunol 2007 : In chronic inflammation, ligand bound PPARalpha represses production of IFNgamma and IL-17 by CD4 ( + ) T cells, and PPARgamma ligands modulate dendritic cell function to elicit the development of anergic CD4 ( + ) T cells