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CTTN — EGF

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CTTN → EGF (increases) Olsen et al., Cell 2006*
  Evidence: We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database

Text-mined interactions from Literome

Goi et al., EMBO J 2000 : These results identify a role for Ral-GTPases in the activation of c-Src by EGF receptors and the coupling of EGF to transcription through Stat3 and the actin cytoskeleton through cortactin
Head et al., Mol Biol Cell 2003 : Phosphorylation of cortactin tyrosine 421 and 466 was elevated in response to Src, epidermal growth factor receptor and Rac1 activation , and tyrosine 421 phosphorylated cortactin localized with F-actin in lamellipodia and podosomes
De Kimpe et al., Cell Signal 2009 : Moreover, there was no effect of PKD mediated cortactin phosphorylation on EGF receptor degradation and LPA induced migration
Desmarais et al., Cell Motil Cytoskeleton 2009 (Breast Neoplasms) : They form in response to epidermal growth factor (EGF) , and contain the usual invadopodium core proteins N-WASP, Arp2/3, cortactin , cofilin, and F-actin
Mader et al., Cancer Res 2011 (Breast Neoplasms...) : In this study, we provide evidence that the Abl related nonreceptor tyrosine kinase Arg mediates epidermal growth factor (EGF) induced cortactin phosphorylation, triggering actin polymerization in invadopodia, ECM degradation, and matrix proteolysis dependent tumor cell invasion
Damiano et al., Oncogene 2012 (Adenocarcinoma...) : p140Cap over-expression affects EGFR signaling and tyrosine phosphorylation of cortactin in response to EGF stimulation