Halpern et al., J Pediatr Gastroenterol Nutr 2003
(Disease Models, Animal...) :
We have shown in previous studies that proinflammatory interleukin-18 and interleukin-12 are up-regulated in the ileum of rats with experimental NEC and that epidermal growth factor (EGF) reduces the development of disease
Shi et al., J Immunol 1997
:
IL-2 also induced apoptosis in normal IL-2-responsive human T cell blasts in the absence of serum, and furthermore, epidermal growth factor and fibroblast growth factor induced increased rates of apoptosis in fibroblasts in the absence of serum, suggesting that cytokine induced apoptosis in the absence of serum survival factors might represent an important biologic phenomenon