Liu et al., Cancer Res 2003
(Lung Neoplasms...) :
In this study, we test the possibility that HDAC inhibitor may increase RECK expression to inhibit MMP activation and cancer cell invasion
Wang et al., J Cereb Blood Flow Metab 2011
(Brain Edema...) :
Our findings suggest that BBB protection by VPA involves HDAC inhibition mediated suppression of NF-?B activation, MMP-9 induction, and tight junction degradation
Shimizu-Hirota et al., Genes Dev 2012
:
In turn, MT1-MMP dependent PI3Kd activation regulates the immunoregulatory Mi-2/NuRD nucleosome remodeling complex that is responsible for controlling macrophage immune response