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PI3 — TLR2

Text-mined interactions from Literome

Guiducci et al., J Exp Med 2008 : Phosphatidylinositol-3 kinase (PI3K) has been shown to be activated by TLR triggering in multiple cell types ; however, its role in pDC function is not known
Watarai et al., Proc Natl Acad Sci U S A 2008 : However, when coupled with Sema6D, a ligand for Plexin-A1, limited TLR-stimulation resulted in PDC-TREM mediated DAP12 dependent phosphorylation of phosphoinositide 3-kinase (PI3K) and extracellular regulated kinase (Erk) 1/2 at 6-9 h, and IFN-alpha was produced
Rex et al., Thromb Haemost 2009 (Thrombosis) : Stimulation of the immune Toll-like receptor 2 (TLR2) on the platelet surface, activates phosphoinositide-3-kinase (PI3K) and causes platelet activation and platelet dependent thrombosis