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MED23 — TP53
Text-mined interactions from Literome
Liu et al., J Biol Chem 2004
:
However, the effect of Aurora-A on
p53 DNA binding and transactivation activity was not
affected by phosphorylation of Ser-315, a recently identified Aurora-A phosphorylation site of p53 ( Katayama, H., Sasai, K., Kawai, H., Yuan, Z. M., Bondaruk, J., Suzuki, F., Fujii, S., Arlinghaus, R. B., Czerniak, B. A., and Sen, S. ( 2004 )
Nat
Radhakrishnan et al., Cancer Res 2006
(Neoplasms...) :
Although
ARC promoted the accumulation of
p53 , ARC induced apoptosis in tumor cells was p53 independent, suggesting that it may be useful for the treatment of tumors with functionally inactive p53
Li et al., Aging Cell 2007
:
Aging up-regulated expression of Bax, Bcl2 and
ARC , down-regulated XIAP expression and did not
affect p53 , pp53 and Omi/HtrA2