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POU5F1 — TP53
Text-mined interactions from Literome
Campayo et al., Eur Respir J 2013
:
miR-145 regulates SOX2 and
OCT4 translation and
p53 regulates miR-145 expression
Jackson et al., Cell cycle (Georgetown, Tex.) 2013
(Ovarian Neoplasms) :
Reduction of
TP53 using sh- or si-RNA
prevented the upregulation of
OCT4A and P21CIP1 and increased DNA damage
Gutekunst et al., Cancer Res 2013
(Neoplasms, Germ Cell and Embryonal...) :
We previously showed that p53 is a major player in cisplatin hypersensitivity and therefore investigated whether
Oct-4 may directly
affect p53 activity
Ren et al., Int J Oncol 2013
(Prostatic Neoplasms) :
Moreover,
WT-p53 also
suppressed colony formation, tumor sphere formation and expression of CSC markers and stemness factors including CD44,
Oct4 , c-Myc and Klf4 in PC-3 cells