Gene interactions and pathways from curated databases and text-mining

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CDCA7 — EPHB2

Text-mined interactions from Literome

Dent et al., Hepatology 2005 : Deoxycholic acid ( DCA ), chenodeoxycholic acid ( CDCA ) , taurodeoxycholic acid ( TDCA ), glycodeoxycholic acid ( GDCA ), taurochenodeoxycholic acid ( TCDCA ), glycochenodeoxycholic acid ( GCDCA ), taurocholic acid ( TCA ), glycocholic acid (GCA), and tauroursodeoxycholic acid ( TUDCA ) all activated ERK1/2 in primary rat hepatocytes that was abolished by inhibition of ERBB1, and significantly reduced by ROS quenching agents ... Treatment of rat hepatocytes with pertussis toxin ( PTX ) did not alter ERK1/2 and AKT activation induced by DCA or CDCA but abolished pathway activations by conjugated bile acids
Yui et al., Nutr Cancer 2009 : At 200 microM, DCA and CDCA induced the phosphorylation of Akt and ERK1/2 , although these phosphorylations do not appear to be indispensable for the cytoprotection