◀ Back to EPHB2
CDCA7 — EPHB2
Text-mined interactions from Literome
Dent et al., Hepatology 2005
:
Deoxycholic acid ( DCA ),
chenodeoxycholic acid ( CDCA ) , taurodeoxycholic acid ( TDCA ), glycodeoxycholic acid ( GDCA ), taurochenodeoxycholic acid ( TCDCA ), glycochenodeoxycholic acid ( GCDCA ), taurocholic acid ( TCA ), glycocholic acid (GCA), and tauroursodeoxycholic acid ( TUDCA ) all
activated ERK1/2 in primary rat hepatocytes that was abolished by inhibition of ERBB1, and significantly reduced by ROS quenching agents ... Treatment of rat hepatocytes with pertussis toxin ( PTX ) did not alter
ERK1/2 and AKT activation
induced by DCA or
CDCA but abolished pathway activations by conjugated bile acids
Yui et al., Nutr Cancer 2009
:
At 200 microM, DCA and
CDCA induced the phosphorylation of Akt and
ERK1/2 , although these phosphorylations do not appear to be indispensable for the cytoprotection