◀ Back to MMP13
MMP13 — MMP3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Ala-Aho et al., Int J Cancer 2002
(Carcinoma, Squamous Cell...) :
The enhanced invasion capacity of
MMP-13 expressing HT-1080 cells was
dependent on
MMP activity, as it was blocked by MMP inhibitor Batimastat ( BB-94 ) and tissue inhibitor of metalloproteinases-3 ( TIMP-3 )
Higashiyama et al., Hepatology 2007
(Liver Cirrhosis...) :
Whereas
MMP-13 was transiently expressed mainly in the cells clustering in the periportal areas,
MMP-9 expression and enzymatic activity were
detected over the resolution process in several different kinds of cells located in the portal areas and along the fibrous septa
Choi et al., J Neurochem 2008
(Nerve Degeneration...) :
Under the cell stress condition,
MMP-3 is released as actMMP-3 rather than the proform ( proMMP-3 ), and catalytically active
MMP-3 added to the medium does not
cause cell death
Kim et al., Rheumatol Int 2012
(Arthritis, Rheumatoid...) :
In conclusion,
MMP-9 and uPA might be
involved in the activation of
pro-MMP-13 through unknown mechanisms in arthritic diseases
Swamydas et al., Cell Adh Migr 2013
(Mammary Neoplasms, Animal...) :
Additionally, the addition of specific
MMP9/MMP13 and MMP14 inhibitors
prevented the
MMP activities of supernatants collected from 4T1 cells incubated with D1CM, CCL5 or CCL9
Coker et al., Am J Physiol 1998
(Heart Failure) :
With pacing CHF, the relative abundance for MMP-1 increased to 319 +/- 94 %,
MMP-2 increased to 194 +/- 31 %, and
MMP-3 increased to 493 +/- 159 % ( all P < 0.05 )
Peeters-Joris et al., Biochim Biophys Acta 1998
(Bone Resorption) :
Furthermore, it was demonstrated that in cultures of mouse calvariae the production of
MMP-13 was
induced by the potent MMP-stimulator heparin and by parathyroid hormone (PTH), whereas the levels of
MMP-3 remained unchanged