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IL10 — SETBP1
Text-mined interactions from Literome
Ji et al., Zhonghua Gan Zang Bing Za Zhi 1999
(Hepatitis B, Chronic) :
Spontaneous,
SEB induced and rHBcAg induced
IL-10 production by PBMCs after culturing in vitro for 48 hours was also higher in patients with CHB ( 280.82 +/- 50.56 ng/L, 321.69 +/- 37.04 ng/L and 369.58 +/- 30.52 ng/L ) than in controls ( 100.2 +/- 8.54 ng/L, 203.41 +/- 12.02 ng/L and 202.38 +/- 15.79 ng/L ; P < 0.01 )
Izeradjene et al., Transplantation 2001
:
MMF treatment decreased tumor necrosis factor alpha, interferon gamma, and
interleukin-10 secretion
induced by
SEB
Sweeney et al., Eur J Vasc Endovasc Surg 2002
(Aortic Aneurysm, Abdominal) :
peripheral T-cell expression of surface markers CD69, CD62L and CD25 in vivo and Interleukin 2 (IL-2) and
Interleukin-10 (IL-10) responses to the superantigen
staphylococcal enterotoxin B (SEB) in vitro were measured preoperatively, 24 h and 1 week postoperatively
Sweeney et al., Br J Surg 2003
(Acute Disease...) :
The production of
interleukin (IL) 10 and IL-2 in vitro in
response to the superantigen
Staphylococcus enterotoxin B (SEB) was assessed
Hisano et al., Arch Dermatol Res 2003
(Dermatitis, Atopic) :
Furthermore, EGCg inhibited
SEB induced TNF-alpha and IFN- gamma production and IL-2, IFN-gamma,
IL-10 and IL-12 p40 mRNA expression in human PBMCs from normal donors in a dose dependent manner
Rowe et al., J Allergy Clin Immunol 2004
(Genetic Predisposition to Disease...) :
In contrast, sensitization was strongly associated with polyclonal IFN-gamma responses to both PHA ( P=.002 ) and SEB ( P=.005 ), and also with
SEB induced IL-5 ( P =.05 ),
IL-10 ( P =.02 ), and IL-13 ( P =.01 )
Sweeney et al., Br J Surg 2005
(Esophageal Neoplasms...) :
There was a significant increase in the production of IL-2 after surgery without a concomitant increase in IFN-gamma or
IL-10 in
response to
SEB
Hayworth et al., Clin Exp Immunol 2009
(Staphylococcal Infections) :
Here, we report that bovine LF ( bLF ) was indeed able to attenuate
SEB induced proliferation,
interleukin-2 production and CD25 expression by human leucocyte antigen ( HLA ) -DR4 transgenic mouse T cells
Teran et al., Clin Immunol 2011
:
Young infants had greater innate immune responses to TLR agonists compared to older children while regulatory responses including
SEB induced
IL-10 and percentages of FoxP3 ( + ) T-regulatory cells decreased with age
Cardell et al., Eur J Immunol 1993
:
High frequencies of cells producing interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) were induced, but very low frequencies of CD4+ T cells produced IL-4, IL-5 or
IL-10 in
response to
SEB ... We further demonstrate that IL-4 and
IL-10 or IFN-gamma production was selectively
induced in resting, high-density CD4+ T cells during primary stimulation, by
SEB + IL-4 or SEB
Tarazona et al., J Immunol 1995
(Shock, Septic) :
Whereas only low, if any, serum IL-10 levels are detectable by ELISA after injection of CPZ, bacterial LPS, or staphylococcal enterotoxin B (SEB) alone, simultaneous administration of CPZ + LPS or CPZ +
SEB causes a significant increase in
IL-10 production in vivo
Höidén et al., Scand J Immunol 1993
:
The cells that had been induced to produce mainly IFN gamma during the primary
SEB stimulation, or during
stimulation with IL4 and
IL10 , synthesized the same lymphokines at restimulation, regardless of stimuli and were unaffected by exogenous IL4
Florquin et al., J Immunol 1994
(Shock, Septic) :
In the present study, we show that
SEB also
triggers the systemic release of
IL-10 , an anti-inflammatory and immunosuppressive cytokine ... Cell depletion experiments and analysis of IL-10 mRNA expression indicated that CD4+ cells played a major role in
SEB induced
IL-10 production ... We conclude that
SEB induces the production of
IL-10 by CD4+ cells in vivo and that endogenous IL-10 plays an important immunoregulatory role in this model by down regulating IL-2 and IFN-gamma production
Bourrié et al., Immunology 1996
(Shock, Septic) :
In mice, the drug confers a potent protection against the lethality induced by SEB, stimulates the
SEB induced serum release of
interleukin (IL)-10 and inhibits at the same time the systemic release of IL-2, IL-4, granulocyte-macrophage colony stimulating factor ( GM-CSF ), IL-6 and tumour necrosis factor-alpha (TNF-alpha)
Kuschnaroff et al., Scand J Immunol 1997
:
However,
SEB induced IL-2 and
IL-10 mRNA expression was suppressed only by CsA, whereas tumour necrosis factor-alpha (TNF-alpha) was decreased only by anti-IFN-gamma Abs
Haskó et al., Eur J Immunol 1998
(Inflammation) :
SEB ( 100 microg )
induced the release of
IL-10 in control C57BL/6 [ IL-10 wild type ( WT ) ] mice, but not in their IL-10 KO counterparts
Perrin et al., Blood 1999
:
Associated with the inhibition of the cell cycle,
IL-10 suppressed
SEB induction of interleukin-2 (IL-2)