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CD151 — MMP9
Text-mined interactions from Literome
Hong et al., J Biol Chem 2006
(MAP Kinase Signaling System...) :
Also,
CD151 induced
MMP-9 expression was shown to be mediated by c-Jun binding to AP-1 sites in the MMP-9 gene promoter, indicating AP-1 activation by CD151 signaling pathways ... The homophilic interactions of
CD151 increased motility and
MMP-9 expression of CD151 transfected MelJuSo cells, along with FAK-, Src-, p38 MAPK-, and JNK mediated activation of c-Jun in an adhesion dependent manner
Shi et al., Hepatology 2010
(Carcinoma, Hepatocellular...) :
CONCLUSION : Overexpression of
CD151 up-regulated the expression of
MMP9 through the PI3K/Akt/GSK-3beta/Snail pathway
Yue et al., Eur J Cancer 2013
(Adenocarcinoma...) :
CD151 more efficiently than Tspan8 recruiting and
activating MMP9 and MMP13 creates a path for migrating tumour cells