Gene interactions and pathways from curated databases and text-mining

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CD151 — MMP9

Text-mined interactions from Literome

Hong et al., J Biol Chem 2006 (MAP Kinase Signaling System...) : Also, CD151 induced MMP-9 expression was shown to be mediated by c-Jun binding to AP-1 sites in the MMP-9 gene promoter, indicating AP-1 activation by CD151 signaling pathways ... The homophilic interactions of CD151 increased motility and MMP-9 expression of CD151 transfected MelJuSo cells, along with FAK-, Src-, p38 MAPK-, and JNK mediated activation of c-Jun in an adhesion dependent manner
Shi et al., Hepatology 2010 (Carcinoma, Hepatocellular...) : CONCLUSION : Overexpression of CD151 up-regulated the expression of MMP9 through the PI3K/Akt/GSK-3beta/Snail pathway
Yue et al., Eur J Cancer 2013 (Adenocarcinoma...) : CD151 more efficiently than Tspan8 recruiting and activating MMP9 and MMP13 creates a path for migrating tumour cells