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CD40LG — MMP9

Text-mined interactions from Literome

Gotoh et al., J Rheumatol 2004 (Arthritis, Rheumatoid...) : CD40-CD154 interaction augments the expression of inflammatory cytokines and MMP in chondrocytes and contributes to an intrinsic process of cartilage degradation in RA
Rahman et al., Inflamm Res 2012 (Disease Models, Animal...) : The MMP inhibitor reduced sepsis induced release of CD40L and maintained normal levels of CD40L on platelets
Schönbeck et al., Circ Res 1997 (Arteriosclerosis...) : Recombinant human CD40L ( rCD40L ) induced de novo synthesis of MMP-1, MMP-3, and MMP-9 on vascular SMCs and stimulated the expression of these enzymes to a greater extent than did maximally effective concentrations of tumor necrosis factor-alpha or interleukin-1beta, established agonists of MMP expression
Wassenaar et al., Clin Exp Immunol 1999 : Therefore, we analysed the CD40L induced MMP production by these fibroblasts in the presence of cytokines that are increased in periodontal lesions, such as IL-1beta, tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma)