Gene interactions and pathways from curated databases and text-mining

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FOXM1 — PTGS2

Text-mined interactions from Literome

Wang et al., Oncogene 2008 (Adenoma...) : Cell culture experiments with A549 human lung adenocarcinoma cells demonstrated that depletion of Foxm1 by either short interfering RNA transfection or treatment with Foxm1 inhibiting ARF 26-44 peptide significantly reduced Cox-2 expression ... In co-transfection experiments, Foxm1 protein induced Cox-2 promoter activity and directly bound to the -2566/-2580 bp region of human Cox-2 promoter
Xu et al., Mol Cancer Res 2013 (Glioma) : In addition, more detailed analysis revealed the involvement of FOXM1 , a member of the forkhead box family of transcriptional activators, in EGF dependent COX-2 induction