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HOXA5 — PTGS2

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: PTGS2 → HOXA5 (decreases, PTGS2 Activity) Rhoads et al., Lymphat Res Biol 2005*
  Evidence: Sustained expression of Hox A5 leads to down regulation of many pro-angiogenic genes including VEGFR2, ephrin A1, Hif1alpha and COX-2.

Text-mined interactions from Literome

Rhoads et al., Lymphat Res Biol 2005 (Breast Neoplasms...) : Sustained expression of Hox A5 leads to down regulation of many pro-angiogenic genes including VEGFR2, ephrin A1, Hif1alpha and COX-2
Blitek et al., J Reprod Dev 2010 : Moreover, HOXA10 dependent expression of prostaglandin H synthase-2 (PGHS-2) , a key enzyme in prostaglandin production, has been previously detected