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MCM7 — SETD2

Text-mined interactions from Literome

Hubbi et al., Mol Cell 2011 : MCM3 inhibits transactivation domain function, whereas MCM7 enhances HIF-1a ubiquitination and proteasomal degradation
Hubbi et al., Science signaling 2013 : In response to hypoxia, HIF-1a bound to Cdc6, a protein that is essential for loading of the minichromosome maintenance (MCM) complex ( which has DNA helicase activity ) onto DNA, and promoted the interaction between Cdc6 and the MCM complex ... Although the interaction between Cdc6 and the MCM complex increased the association of the MCM proteins with chromatin, the binding of HIF-1a to the complex decreased phosphorylation and activation of the MCM complex by the kinase Cdc7