Gene interactions and pathways from curated databases and text-mining

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TNF — TSHR

Text-mined interactions from Literome

Valyasevi et al., J Clin Endocrinol Metab 2001 (Graves Disease) : We found that each of these cytokines inhibits TSH dependent cAMP production and TSHr gene expression, and that TNF-alpha and IFN-gamma also inhibit morphological adipocyte differentiation
Douglas et al., J Clin Endocrinol Metab 2010 (Graves Ophthalmopathy) : They express TSHR at high levels and TSH induces fibrocytes to produce IL-6 and TNF-alpha