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ID1 — TP53

Text-mined interactions from Literome

Pammer et al., Endothelium : journal of endothelial cell research 2004 : These experiments demonstrate for the first time that Id1 can be up-regulated and p53 down-regulated by a statin in HDMECs
Tepper et al., Prostate 2005 (Neoplasms, Hormone-Dependent...) : p53GOF mediated regulation of Id-1 expression was validated by RT-PCR and dual-luciferase reporter assays
McNeely et al., Environ Health Perspect 2006 : p53 promotes mitotic exit and leads to more extensive ID1 induction by arsenite
Kim et al., Breast Cancer Res Treat 2008 (Breast Neoplasms) : Taken together, we present a molecular mechanism where Id-1 regulates p53 and NF-kappaB pathways, which in turn regulates Bax and Bcl-2 genes, thus providing a survival advantage under exogenous stress such as serum-free or taxol treatment in MCF-7 breast cancer cells
Lee et al., Oncogene 2009 (Breast Neoplasms) : Id-1 negatively regulated both p53 and PTEN at the transcriptional level ... In promoter assay with serial deletion and chromatin immunoprecipitation assay, the binding of p53 to the PTEN promoter was reduced by Id-1 , suggesting that Id-1 regulates PTEN transcription through its p53 modulation