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OPN1LW — TP53

Text-mined interactions from Literome

Ikeda et al., Biochem Biophys Res Commun 2000 : However, we found that the inhibition by RelA of p53 transcriptional activity is not completely restored by CBP/p300 overexpression and that a p53 mutant can not suppress RelA activity despite of its ability to bind CBP/p300
Nakazawa et al., Int J Mol Med 2002 (Arthritis, Rheumatoid) : Overexpression of CBP induced p53 transcriptional activity and recovery of TNFalpha induced inhibition
Poulin et al., J Virol 2004 : We demonstrate that SV40 T Ag is acetylated in vivo in a p53 dependent manner and T Ag acetylation is largely mediated by CBP
Fuchs-Young et al., Breast Cancer Res Treat 2011 (Cell Transformation, Neoplastic...) : Previous studies from our laboratory have shown that p53 regulates ER expression transcriptionally, by binding the ER promoter and forming a complex with CARM1, CBP , c-Jun, RNA polymerase II and Sp1
Borah et al., Chem Biol 2011 (Myocardial Ischemia) : p53 activation is dependent on lysine acetylation by the lysine acetyltransferase and transcriptional coactivator CREB binding protein (CBP) and on acetylation directed CBP recruitment for p53 target gene expression
Vaughan et al., Arch Biochem Biophys 2012 : p53 mutants induce transcription of NF-?B2 in H1299 cells through CBP and STAT binding on the NF-?B2 promoter and gain of function activity ... ChIP assays using antibodies against transcription factors putatively capable of interacting with the NF-?B2 promoter show increased interaction of CBP and STAT2 in the presence of mutant p53
Ravi et al., Cancer Res 1998 : p53 dependent transactivation and transrepression require its interaction with p300/CBP , a coactivator that also interacts with the RelA subunit of nuclear factor-kappaB
Lambert et al., J Biol Chem 1998 : Remarkably, we now demonstrate that phosphorylation of p53 at Ser15 increases its ability to recruit CBP/p300