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IGF1 — PPP1R3A
Text-mined interactions from Literome
Chen et al., Br J Pharmacol 2006
:
The results indicate that
Rg1 significantly
increases IGF-IR expression and
IGF-IR promoter activity in MCF-7 cells ( P < 0.05 ) ... Taken together, our results suggest that
Rg1 not only
increases IGF-IR expression but also enhances IGF-IR mediated signaling pathways in MCF-7 cells ... The
stimulation of
IGF-IR expression by
Rg1 in MCF-7 cells appears to require ER, and its actions might involve ligand independent activation of ER
Li et al., Zhong Xi Yi Jie He Xue Bao 2008
(Brain Injuries) :
[
Effects of ginsenoside
Rg1 on expression of
insulin-like growth factor-1 in brain of rats with brain contusion ]
Lau et al., Br J Pharmacol 2009
(Breast Neoplasms...) :
The
effects of
Rg1 on cell proliferation and
IGF-IR protein expression were studied in the presence of tyrosine kinase inhibitor genistein to elucidate the involvement of tyrosine kinase in mediating these effects ...
Rg1 induction of cell proliferation and
IGF-IR protein expression was abolished by co-treatment with genistein