Gene interactions and pathways from curated databases and text-mining

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HSP90AA1 — IL1B

Text-mined interactions from Literome

Kanzaki et al., Biochem Biophys Res Commun 2003 : Telomerase upregulates expression levels of interleukin (IL)-1alpha, IL-1beta , IL-6, IL-8, and granulocyte-macrophage colony stimulating factor in normal human fibroblasts
Broemer et al., Oncogene 2004 (Inflammation...) : Short-time inhibition of Hsp90 resulted in impaired IKK kinase activation by TNFalpha, IL-1beta or phorbolester PMA
Jia et al., Cardiovasc Res 2006 (Sepsis) : Use of specific pharmacologic inhibitors and short interference RNA revealed that Hsp90 was required for IL-1beta to downregulate VLDL-R expression
Boehm et al., Arthritis Rheum 2007 : Hsp90 mediates insulin-like growth factor 1 and interleukin-1beta signaling in an age dependent manner in equine articular chondrocytes ... The aim of this study was to investigate the roles of age and Hsp90 in insulin-like growth factor 1 (IGF-1) and interleukin-1beta (IL-1beta) signaling in chondrocytes