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CTNNB1 — SRY

Text-mined interactions from Literome

Paoni et al., Physiol Genomics 2003 (Adenoma...) : SRY-box containing gene 17 (Sox 17) , a negative regulator of beta-catenin signaling, and calbindin-D9K, a factor that enhances calcium transport, were more highly expressed in adenomas than carcinomas ( approximately 4-fold and 15- to 22-fold, respectively )
Bernard et al., Int J Biochem Cell Biol 2008 (Disorders of Sex Development) : We hypothesize that SRY prevents Wnt/beta-catenin signaling, thereby inhibiting ovarian development ... Thus SRY inhibition of beta-catenin involves neither DNA binding nor transactivation functions of SRY
Tamashiro et al., Biochim Biophys Acta 2008 : To seek a possible interaction between male and female sex determination mechanisms, we examined whether Sry affects Wnt/beta-catenin signaling ... Using the TOPFLASH reporter system to measure Lef/Tcf dependent transcriptional activity, we showed that ectopic expression of mouse Sry strongly suppressed Wnt/beta-catenin signaling in mouse embryonal carcinoma and human embryonic kidney cell lines