Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
TLR3 ▸ ICAM1 ▸ NM ▸ TLR5 ▸ PTGS2 ▸ CD40 ▸ IL13 ▸
VEGFA ▸ AHSA1 ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ TLR7 ▸
IL3 ▸ TLR8 ▸ TLR6 ▸ RNF19A ▸ IL15 ▸ IL33 ▸ IL5 ▸
TLR10 ▸ TGFB1 ▸ LTA ▸ F2RL1 ▸ IL18 ▸ NOS2 ▸ TCF21 ▸
TCF4 ▸ TCF25 ▸ TCF23 ▸ TCF24 ▸ TCF15 ▸ TCF7 ▸ TCF19 ▸
TCF3 ▸ TCF20 ▸ IL22 ▸ TCF12 ▸ CRK ▸ NFKBIA ▸ PIK3R1 ▸
PIK3CA ▸ NA ▸ CSE ▸ LPA ▸ MMP9 ▸ IL32 ▸ IL1RN ▸
CDC73 ▸ PAF1 ▸ LEO1 ▸ IL31 ▸ GRAP2 ▸ EGF ▸ APOB ▸
HGF ▸ WDR61 ▸ CTR9 ▸ IFNB1 ▸ CXCR1 ▸ MMP2 ▸ IL7 ▸
IL11 ▸ S100A8 ▸ IL21 ▸ IL19 ▸ FGF2 ▸ IL16 ▸ ITGAM ▸
IL20 ▸ IL9 ▸ IL25 ▸ IL37 ▸ IL34 ▸ IL24 ▸ IL27 ▸
MMP3 ▸ FAS ▸ SAA1 ▸ POLDIP2 ▸ INS ▸ IL26 ▸ NOS1 ▸
MIF ▸ EGFR ▸ CXCR2 ▸ ALB ▸ PI3 ▸ CRP ▸ AKT1 ▸
AKT2 ▸ AKT3 ▸ CALM3 ▸ MMP1 ▸ CASP3 ▸ CD14 ▸ CASP4 ▸
NOX1 ▸ IKBKB ▸ MMP13 ▸ CASP16 ▸ NOS3 ▸ CASP2 ▸ CASP9 ▸
CASP6 ▸ CASP5 ▸ F2R ▸ CASP10 ▸ CASP1 ▸ CASP14 ▸ CASP8 ▸
CASP7 ▸ CASP12 ▸ CD40LG ▸ NOX4 ▸ PTX3 ▸ PLG ▸ NOX5 ▸
HMGB1 ▸ NOX3 ▸ SELE ▸ CHUK ▸ IGF1 ▸ LIF ▸ MYLIP ▸
ITGB2 ▸ TGFB2 ▸ PTK2 ▸ MYD88 ▸ PTK6 ▸ TNFSF10 ▸ NOD1 ▸
PTK7 ▸ MMP8 ▸ GP6 ▸ GP9 ▸ IL12B ▸ MAP3K7 ▸ TREM1 ▸
CXCL12 ▸ PRG2 ▸ ERVK-6 ▸ IFNA2 ▸ PTX4 ▸ GP2 ▸ LEP ▸
STAT3 ▸ GP5 ▸ IKBKG ▸ MUC1 ▸ SRC ▸ PRG3 ▸ PRG4 ▸
VIP ▸ PAM ▸ PLD2 ▸ SERPINE1 ▸ IFNA1 ▸ PRKAR1B ▸ SOD3 ▸
SOD1 ▸ CRH ▸ VCAM1 ▸ IFNA14 ▸ PRKAR1A ▸ HNRNPH1 ▸ IFNA17 ▸
IFNA6 ▸ S100A12 ▸ PRKAR2B ▸ HNRNPF ▸ IFNA7 ▸ WNK1 ▸ MMP7 ▸
IFNA10 ▸ IFNA8 ▸ MPO ▸ PTBP2 ▸ SOD2 ▸ IFNA4 ▸ PTBP1 ▸
IFNA21 ▸ IFNA16 ▸ PRKAR2A ▸ MMP14 ▸ IFNA5 ▸ IL12A ▸ CSF3 ▸
PRKACB ▸ IFNA13 ▸ PRKACG ▸ HDAC2 ▸ LTB ▸ MMP17 ▸ MMP20 ▸
PLD1 ▸ MMP10 ▸ MMP28 ▸ EDN1 ▸ CXCL10 ▸ ELANE ▸ MMP15 ▸
MSH3 ▸ MMP24 ▸ IL1R1 ▸ CAT ▸ EGR1 ▸ MMP25 ▸ HDAC1 ▸
FGF1 ▸ MMP11 ▸ NOD2 ▸ TNFRSF1A ▸ CSK ▸ MMP26 ▸ SETD2 ▸
TGFB3 ▸ MMP12 ▸ MMP27 ▸ MMP21 ▸ MMP19 ▸ CCL3 ▸ MMP16 ▸
SPP1 ▸ NAALADL1 ▸ PLA2G1B ▸ MSH2 ▸ MSH5 ▸ MSH6 ▸ ANGPT2 ▸
SST ▸ FGF7 ▸ PLD5 ▸ SYT1 ▸ FASLG ▸ PLD4 ▸ PLD3 ▸
QRICH2 ▸ AHR ▸ TRAF6 ▸ MSH4 ▸ MAP2K1 ▸ TAB1 ▸ QRICH1 ▸
CD4 ▸ PLD6 ▸ CD8A ▸ CSF1 ▸ CD46 ▸ SOCS3 ▸ FGF19 ▸
FGF23 ▸ HMOX1 ▸ FGF9 ▸ STX2 ▸ FGF3 ▸ C1QA ▸ CD28 ▸
TXN ▸ FGF10 ▸ FGF22 ▸ HDAC3 ▸ SELP ▸ FGF16 ▸ PPARG ▸
FGF8 ▸ FGF12 ▸ FGF18 ▸ HDAC6 ▸ TNFSF12 ▸ FGF4 ▸ FGF14 ▸
CSRP1 ▸ C1QB ▸ SELL ▸ HDAC5 ▸ LTF ▸ CXCL1 ▸ FGF20 ▸
FGF6 ▸ RAC1 ▸ NGF ▸ HSPD1 ▸ SAA2 ▸ ADIPOQ ▸ FGF5 ▸
PDLIM7 ▸ ITGB1 ▸ P2RY6 ▸ ETS1 ▸ FGF17 ▸ FGF13 ▸ FGF11 ▸
STAT1 ▸ CD38 ▸ FGF21 ▸ MTOR ▸ HES1 ▸ GPI ▸ STAT4 ▸
CD79A ▸ BCL3 ▸ IL2RA ▸ HDAC7 ▸ RHOA ▸ CXCR3 ▸ MUC15 ▸
APC ▸ SAA4 ▸ PF4 ▸ HDAC8 ▸ HSPG2 ▸ MUC17 ▸ NAP1L4 ▸
HSPB1 ▸ MUC8 ▸ TAT ▸ HDAC9 ▸ CD8B ▸ SETBP1 ▸ AGTR2 ▸
MUC16 ▸ MUC4 ▸ ANG ▸ MUC20 ▸ CISH ▸ STX1A ▸ PDGFB ▸
MTX1 ▸ HDAC10 ▸ MUC22 ▸ HDAC11 ▸ ECM2 ▸ TNFSF13B ▸ PPARA ▸
RBBP4 ▸ CPOX ▸ NPS ▸ PRKCD ▸ CXCR4 ▸ MUC6 ▸ ST8SIA2 ▸
TRPV1 ▸ HDAC4 ▸ RHO ▸ CR1 ▸ MUC7 ▸ PLA2G4A ▸ PLAU ▸
MUC13 ▸ MUC19 ▸ ECM1 ▸ TNMD ▸ RBBP7 ▸ ITIH4 ▸ CFTR ▸
PDCD11 ▸ MUC21 ▸ PRTN3 ▸ MUC12 ▸ MUC2 ▸ ANGPT1 ▸ TAC3 ▸
PRR13 ▸ PRR19 ▸ PGD ▸ UTP3 ▸ SIGLEC7 ▸ IL1R2 ▸ PRKAA1 ▸
HES2 ▸ PRR26 ▸ PRL ▸ BCL10 ▸ PRKAA2 ▸ UTP20 ▸ HES5 ▸
MUC5AC ▸ HES6 ▸ PRR5 ▸ NR0B1 ▸ IBD5 ▸ IRAK1 ▸ CXCL11 ▸
PRR3 ▸ CALM2 ▸ TF ▸ ICAM3 ▸ IFI44 ▸ PRR21 ▸ OSM ▸
TAC1 ▸ UTP18 ▸ CTNNB1 ▸ ARG1 ▸ MET ▸ SELPLG ▸ PTAFR ▸
FCGR1A ▸ RELB ▸ PRKAG1 ▸ PRR18 ▸ IBD8 ▸ PRR22 ▸ ICAM5 ▸
MT3 ▸ HES4 ▸ IBD3 ▸ EPO ▸ ARG2 ▸ IBD6 ▸ MPL ▸
PRR24 ▸ TGFA ▸ IBD2 ▸ RENBP ▸ IBD4 ▸ ELF3 ▸ HDC ▸
BRAF ▸ ESR1 ▸ PRKCA ▸ TAC4 ▸ DEFA1 ▸ TPO ▸ FGA ▸
PRR12 ▸ PRR14 ▸ SMAD3 ▸ CHI3L1 ▸ PRR11 ▸ FGG ▸ CXCL9 ▸
PRKAB2 ▸ PKD1 ▸ LPL ▸ HES3 ▸ NR4A2 ▸ ADCYAP1 ▸ IRAK3 ▸
UTP23 ▸ SEA ▸ FOXO3 ▸ HES7 ▸ CXCL6 ▸ TP53 ▸ ETS2 ▸
CALM1 ▸ NTS ▸ MAP2K7 ▸ PRR7 ▸ GRP ▸ ICAM4 ▸ PGF ▸
DDIT3 ▸ ADAM11 ▸ ROCK2 ▸ PRKAG2 ▸ UTP6 ▸ CXCL17 ▸ APEX1 ▸
ICOSLG ▸ PRR15 ▸ AZU1 ▸ CYP1A1 ▸ PRR9 ▸ BCL2 ▸ PAEP ▸
CCL20 ▸ MT4 ▸ A2M ▸ HBEGF ▸ ELF4 ▸ TFPI ▸ IBD7 ▸
PRKAB1 ▸ RNASE3 ▸ PRDX2 ▸ EMD ▸ ADAM17 ▸ PRR16 ▸ DUSP1 ▸
IBD9 ▸ CCR5 ▸ ICAM2 ▸ PRR25 ▸ MAP3K1 ▸ NUP43 ▸ JAK2 ▸
UTP15 ▸ IL17F ▸ PRR4 ▸ CD44 ▸ PAK1 ▸ CSTA ▸ PARK2 ▸
FUT5 ▸ PARK7 ▸ CTGF ▸ WNT3 ▸ RAC3 ▸ CPB2 ▸ C1orf228 ▸
IL23A ▸ CX3CL1 ▸ SMAD1 ▸ KLRB1 ▸ PAK2 ▸ FOSL1 ▸ ASIP ▸
FOXP3 ▸ SLPI ▸ CSH1 ▸ CAPN7 ▸ ADM ▸ MEFV ▸ WNT16 ▸
IFIH1 ▸ CD69 ▸ ITGA5 ▸ ACKR3 ▸ HCG15 ▸ TNP2 ▸ MAP2K2 ▸
CD83 ▸ CAPN2 ▸ DNASE2 ▸ FGFR2 ▸ PDGFA ▸ CEACAM1 ▸ PAK4 ▸
IRS1 ▸ RAG1 ▸ FUT4 ▸ DNASE1 ▸ FCER2 ▸ CCL5 ▸ NLRP3 ▸
CXCR6 ▸ MAP2K5 ▸ CAPN1 ▸ MTA3 ▸ PTHLH ▸ PGP ▸ APOA1 ▸
PROK1 ▸ SPESP1 ▸ TPT1 ▸ PAK3 ▸ DPM1 ▸ VCP ▸ CAPN8 ▸
CGN ▸ ELF5 ▸ HCG27 ▸ CEBPA ▸ FUT2 ▸ PDCD4 ▸ CXCL14 ▸
HCG24 ▸ FUT7 ▸ SERPINE2 ▸ PAH ▸ MBP ▸ TNFRSF9 ▸ TRNAI1 ▸
SFXN1 ▸ GHRH ▸ APOE ▸ NPY ▸ CEBPB ▸ HCG22 ▸ SOAT1 ▸
CNR1 ▸ ATP8A2 ▸ CD86 ▸ NPY4R ▸ ALX3 ▸ HCG23 ▸ F7 ▸
NFKBIZ ▸ MYO19 ▸ BLM ▸ APOA2 ▸ KRT10 ▸ ABL1 ▸ PTPN22 ▸
TEC ▸ CP ▸ ALX4 ▸ FUT8 ▸ GRB10 ▸ CXCL5 ▸ TRAF2 ▸
CTSB ▸ CDH5 ▸ S100A9 ▸ MYO16 ▸ DPM3 ▸ HRAS ▸ GRB14 ▸
HCG8 ▸ MYO6 ▸ WNT4 ▸ ALOX5 ▸ UCN2 ▸ MAP2K4 ▸ SMAD4 ▸
RETN ▸ TNFSF11 ▸ ADAM19 ▸ CA1 ▸ NR4A1 ▸ HMGB2 ▸ GSTM1 ▸
HRH1 ▸ CAPN3 ▸ DEFA1B ▸ PINK1 ▸ ALX1 ▸ POU2F1 ▸ OXA1L ▸
IGF2 ▸ HMGB3 ▸ CDC42 ▸ TBP ▸ HCG18 ▸ MAP2K6 ▸ CCL4 ▸
HCG20 ▸ ELF1 ▸ TMSB4X ▸ F10 ▸ CEACAM6 ▸ DUOX1 ▸ TNPO1 ▸
ELAVL1 ▸ NAMPT ▸ SMAD9 ▸ FOXO1 ▸ GIP ▸ JAK3 ▸ FUT1 ▸
CAPN10 ▸ FGB ▸ PTGS1 ▸ RNASE2 ▸ CD1D ▸ AGTR1 ▸ DDX58 ▸
AR ▸ CXCL16 ▸ SERPINB2 ▸ AREG ▸ IDO1 ▸ CTSS ▸ SMAD6 ▸
MAPKAPK2 ▸ FXYD1 ▸ FUT6 ▸ CAPN15 ▸ MTA1 ▸ BPI ▸ KLK3 ▸
PTPN11 ▸ FCGR2B ▸ CAPN6 ▸ PITX1 ▸ SMAD7 ▸ GAST ▸ MTA2 ▸
CPB1 ▸ SMAD5 ▸ CXCL13 ▸ CAPN11 ▸ SPP2 ▸ HCG14 ▸ CDH1 ▸
ARSA ▸ FOXO4 ▸ MEPE ▸ BCL6 ▸ CYP19A1 ▸ TACR1 ▸ MRXS5 ▸
CXCL2 ▸ C3 ▸ CXCL3 ▸ GRPR ▸ GAL ▸ HCG4 ▸ ADAM10 ▸
CSH2 ▸ STAT5A ▸ HCG9 ▸ HCG11 ▸ SYK ▸ HCG17 ▸ CAPN5 ▸
HLA-DRB1 ▸ HCG21 ▸ REL ▸ WNT11 ▸ ANPEP ▸ BCR ▸ MKNK1 ▸
MPG ▸ HCG16 ▸ JAK1 ▸ HCG25 ▸ KDR ▸ FUT3 ▸ CAPN14 ▸
VASP ▸ MYO10 ▸ BMP2 ▸ CD163 ▸ FMR1 ▸ VDR ▸ CAPN9 ▸
WNT6 ▸ CAPN13 ▸ GRB2 ▸ HMGB4 ▸ TNP1 ▸ ELF2 ▸ NPY6R ▸
FOXO6 ▸ CYP1A2 ▸ FUT11 ▸ CD2 ▸ ROCK1 ▸ CNR2 ▸ HCG26 ▸
FUT10 ▸ VAV1 ▸ RABEPK ▸ HBD ▸ GH1 ▸ THBD ▸ FUT9 ▸
HIF1A ▸ LBP ▸ KSR2 ▸ CAPN12 ▸ TSC22D3 ▸ F2RL2 ▸ MAP2K3 ▸
SCARB1 ▸ SMAD2 ▸ PAK7 ▸ GRB7 ▸ TNFRSF1B ▸ WNT2 ▸ DPM2 ▸
WNT1 ▸ RAC2 ▸ PAK6 ▸ HCAR1 ▸ NMUR2 ▸ GABBR2 ▸ NMUR1 ▸
PTGER3 ▸ GNAI3 ▸ HEBP1 ▸ TAS2R14 ▸ U2AF1 ▸ SSTR3 ▸ OPRK1 ▸
NPBWR2 ▸ CCR2 ▸ TAS2R31 ▸ CCL27 ▸ MT-RNR2 ▸ GRM7 ▸ KNG1 ▸
DRD3 ▸ SUCNR1 ▸ GPER1 ▸ GNAT3 ▸ TAS2R42 ▸ NMU ▸ CCR7 ▸
TAS2R10 ▸ PYY ▸ PPBP ▸ P2RY4 ▸ CCR1 ▸ CCR10 ▸ GNAI2 ▸
RXFP4 ▸ OXER1 ▸ S1PR2 ▸ HTR1E ▸ MCHR2 ▸ TAS2R45 ▸ GNB1 ▸
CCR8 ▸ PENK ▸ NPY1R ▸ ADRA2A ▸ DRD2 ▸ PTGDR2 ▸ S1PR3 ▸
OPRL1 ▸ MTNR1A ▸ INSL5 ▸ GNG2 ▸ PDYN ▸ CCL19 ▸ DRD4 ▸
TAS2R30 ▸ TAS2R7 ▸ NPB ▸ TAS2R16 ▸ SSTR2 ▸ ADRA2C ▸ RXFP3 ▸
GABBR1 ▸ GRM4 ▸ TAS2R39 ▸ TAS2R46 ▸ GRM2 ▸ FPR1 ▸ CHRM2 ▸
ADORA3 ▸ C5AR1 ▸ HTR5A ▸ C3AR1 ▸ HCAR2 ▸ BDKRB1 ▸ OXGR1 ▸
APLNR ▸ TAS2R41 ▸ HTR1B ▸ TAS2R40 ▸ P2RY12 ▸ GALR2 ▸ PNOC ▸
CX3CR1 ▸ NPY2R ▸ MCHR1 ▸ PPY ▸ MTNR1B ▸ TAS2R8 ▸ TAS2R1 ▸
OPRD1 ▸ TAS2R9 ▸ S1PR1 ▸ XCR1 ▸ CCR4 ▸ HRH4 ▸ CCR6 ▸
TAS2R50 ▸ CCR9 ▸ ADORA1 ▸ S1PR5 ▸ SSTR5 ▸ CHRM4 ▸ DARC ▸
SSTR1 ▸ TAS2R38 ▸ BDKRB2 ▸ HRH3 ▸ TAS2R5 ▸ S1PR4 ▸ CCL16 ▸
GALR1 ▸ TAS2R13 ▸ HTR1F ▸ CCL25 ▸ TAS2R19 ▸ TAS2R20 ▸ P2RY13 ▸
TAS2R3 ▸ GALR3 ▸ PMCH ▸ HCAR3 ▸ TAS2R4 ▸ GNAI1 ▸ ANXA1 ▸
GRM6 ▸ HTR1A ▸ HTR1D ▸ ADRA2B ▸ GRM3 ▸ NPBWR1 ▸ NPY5R ▸
FPR3 ▸ LPAR5 ▸ SSTR4 ▸ TAS2R43 ▸ TAS2R60 ▸ GRM8 ▸ CCL28 ▸
Data information
Please see the Gene Interactions Track Manual.