Gene interactions and pathways from curated databases and text-mining

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IL16 — IL5

Text-mined interactions from Literome

Suchin et al., J Am Acad Dermatol 2001 (Eosinophilia...) : Increased interleukin 5 production in eosinophilic Sézary syndrome : regulation by interferon alfa and interleukin 12
Pinsonneault et al., J Allergy Clin Immunol 2001 (Hypersensitivity, Immediate) : IL-16 inhibits IL-5 production by antigen stimulated T cells in atopic subjects
De Bie et al., Clin Exp Allergy 2002 (Asthma...) : Thirdly, the presence of IL-16 during priming cultures of TCR transgenic T cells ( DO11.10 ), reduces IL-4 ( 33 % ) and IL-5 ( 35 % ), but not IL-10 and IFNgamma levels upon re-stimulation
El Bassam et al., Immunology 2006 (Asthma...) : We have previously shown that IL-16 inhibits IL-5 secretion by allergen stimulated peripheral blood mononuclear cells ( PBMC ) ... Neutralization of IFN-gamma, IL-12, IL-10 or IL-18 did not alter the inhibitory effects of IL-16 on IL-13 and IL-5 secretion by allergen stimulated PBMC ... IL-16 did not modify IL-13 synthesis by anti-CD3 stimulated CD4 ( + ) T cells, but it significantly reduced the production of IL-5
Swain et al., Proc Natl Acad Sci U S A 1981 : We conclude that the C.C3.11.75 TRF activity is not due to interleukin 1 or to interleukin 2 but to a third factor provisionally designated as ( DL ) TRF
Zaitseva et al., Infect Immun 1995 : Gamma interferon ( IFN-gamma ), interleukin-2 (IL-2), IL-4, and IL-5 induction was assayed by mRNA-specific PCR and by enzyme linked immunosorbent assay and bioassay for protein production